- 主题
- 9
- 您的身份
- 病友
- 就诊医院
- 北京肿瘤医院
- 病理报告
- 经典型霍奇金
- 目前状态
- 康复1-3年
参加活动:0 次 组织活动:0 次

您的身份病友
病理报告经典型霍奇金
就诊医院北京肿瘤医院
目前状态康复1-3年
最后登录2017-10-16

|

楼主 |
发表于 2015-3-5 08:02:08
|
显示全部楼层
来自: 中国上海
Abstract
文摘
Objective: To evaluate the role of Fluorine-18-fluorodexoyglucose Positron Emission Tomography (FDG-PET) scan in staging and its implications on the treatment of lymphoma, and to study the concordance between visual assessment and Deauville criteria for the interpretation of interim scans. Methods: The prospective single-arm experimental study was conducted at the Shaukat Khanum Memorial Cancer Hospital, Lahore, from May 2011 to October 2011.1t comprised 53 newly diagnosed lymphoma patients who agreed to participate in the study. All patients underwent scans with contrast-enhanced computerised tomography at baseline. Treatment plan was formulated based on the final stage. Interim scans were acquired after 2 cycles of chemotherapy and were reported using visual criteria and compared with the 5-point Deauville criteria. Score of 13 was taken as disease-negative, while 4-5 was taken as disease-positive. SPSS 19 was used for statistical analysis. Results: Of the 53 patients, 35 (66%) had Hodgkin's Lymphoma, while 18(34%) had Non-Hodgkin's Lymphoma. Scans resulted in disease upstaging in 4 (7.5%) patients, and detecting increased disease burden in 12 (23%). On interim scans, complete remission was achieved in 38(71%) patients (Deauville score 1-3); 12(23%) showed partial response (Deauville score 4-5); and 3 (6%) had progression. Kappa test was statistically significant (kappa 0.856; p<0.001). Conclusion: The positron emission tomography helped to upstage lymphoma and reflected increased disease burden. The Deauville criteria correlated very well with visual assessment criteria and can be applied in the patient population.
目的:评估的角色Fluorine-18-fluorodexoyglucose正电子发射断层扫描(正)在治疗淋巴瘤的分期及其影响,并研究视觉评估与多维尔标准相一致的解释临时扫描。方法:前瞻性随访实验研究Shaukat Khanum纪念癌症医院,拉合尔,从2011年5月到10月2011.1吨由53个新诊断淋巴瘤患者同意参与这项研究。所有患者接受了与计算机电脑扫描基线。制定治疗计划是基于最后阶段。临时扫描获得2周期化疗后,报道使用视觉标准并与平均智商多维尔标准。13分被视作disease-negative,而作为disease-positive 4 - 5。SPSS 19用于统计分析。结果:53例,35(66%)霍奇金淋巴瘤,而18(34%)非霍奇金淋巴瘤。扫描导致疾病4例(7.5%)患者的风头,和检测疾病负担增加12(23%)。临时扫描,38例(71%)患者达到完全缓解(多维尔分数1 - 3),12(23%)显示部分响应(多维尔得分4 - 5);和3例(6%)进展。Kappa测试是统计学意义(卡巴0.856;p < 0.001)。结论:正电子发射断层扫描有助于自负的淋巴瘤和反映疾病负担增加。多维尔标准视觉评估准则的相关性很好,可以应用于病人的人口。
关键词: FDG-PET scan Lymphoma Deauville criteria
关键词:正子摄影淋巴瘤多维尔的标准. |
|