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Sunlight Exposure Reduces Risk of Non-Hodgkin’s Lymphoma, Study Finds 研究发现，晒太阳可以降低非霍奇金淋巴瘤的风险
People with high exposure to sunlight or ultraviolet radiation are significantly less likely to develop non-Hodgkin’s lymphoma compared to those with low exposure, but vitamin D levels in the body have no impact on disease incidence, a new study shows. 一项新的研究显示，经常暴露于阳光或紫外线照射的人相对来说有明显更低的患非霍奇金淋巴瘤的概率，但是体内维生素D的水平与疾病的发生率无关。
这篇名为“维生素D与非霍奇金淋巴瘤：一项更新的荟萃研究”的文章发表在PloS One期刊上。
The incidence of non-Hodgkin’s lymphoma (NHL) — one of the most common blood cancers — has been increasing in the last decade, underscoring the importance of environmental factors in its development. 非霍奇金淋巴瘤是最常见的血液肿瘤之一，其发病率在最近几十年内逐渐上升，环境因素起到了重要的作用。
One of the environmental factors that previously has been shown to be important in NHL is vitamin D. This is especially important as vitamin D deficiency has become a pandemic. 先前发现的一个重要的环境因素是维生素D。这个发现非常重要，因为维生素D缺乏的现象非常普遍。
Vitamin D can be acquired a number of different ways. The most common method is through exposure to sunlight or ambient ultraviolet radiation (UVR), but vitamin D pills may also be used. 维生素D可以通过很多方式来获取。最常见的办法是暴露于阳光或紫外线照射中，不过，也可以服用维生素D药丸。
Prior studies have shown that sunlight exposure has a protective role on the incidence of NHL and its subtypes, but have failed to show an association between dietary vitamin D or the levels of its circulating form 25-hydroxyvitamin D (25(OH)D). 之前的研究显示，阳光照射对非霍奇金淋巴瘤的各个亚型的发生起到保护作用，但是未能证明饮食中的维生素D或其在体内循环中的25-hydroxyvitamin D (25(OH)D)与非霍奇金淋巴瘤的相关性。
Because of the progress that has been made in the classification and diagnosis of NHL, as well as the persistent emphasis on the vitamin D-NHL association, researchers conducted a meta-analysis of published studies to determine the association between vitamin D status and the risk of NHL and all traceable subtypes. 由于在非霍奇金的诊断和分型上不断的进步，以及对维生素D与非霍奇金淋巴瘤的相关性的重视，研究人员进行了一项基于已公布的各项相关研究的荟萃研究，旨在确定维生素D与非霍奇金淋巴瘤和其各个亚型之间的关系。
The goal was to extensively investigate the association between NHL and various measures of vitamin D, including sunlight/UVR exposure, dietary vitamin D intake, and serum 25(OH)D levels. 研究的方向是深入的调查非霍奇金淋巴瘤与维生素D的各个指标，包括阳光/紫外线照射，维生素D的饮食摄取，以及血清25(OH)D水平之间的关系。
Researchers reviewed data from 30 studies, including 56,458 NHL patients. Twenty-four studies investigated the impact of sunlight/UVR exposure, nine examined dietary vitamin D intake, and three looked at serum/plasma 25(OH)D levels. 研究人员对30项相关研究、共56,458位非霍奇金淋巴瘤患者的数据进行了分析。其中有24项研究调查了阳光/紫外线照射的影响，9项研究审视了维生素D饮食摄取，另外还有3项研究考察了血清/血浆25(OH)D水平。
As previously shown, results indicated a significant protective effect of overall sunlight/UVR exposure on NHL and all its subtypes, with a 20% lower risk among patients with high exposure compared to those with low exposure. 正如之前所说的，研究结果显示，阳光/紫外线照射对非霍奇金淋巴瘤及其各个亚型都有显著的保护作用，较高暴露的人群相对于较低暴露的人群风险降低20%。
In contrast, neither dietary vitamin D intake nor serum/plasma 25(OH)D levels had consistent or significant effects on the risk for NHL or any of its subtypes. “A consistent protective effect of sunlight/UVR exposure on NHL and the various subtypes was observed, while inconsistent or non-significant association was found for dietary vitamin D intake and serum/plasma 25(OH)D levels,” researchers concluded. 相比之下，维生素D饮食摄取或血清/血浆25(OH)D水平对于非霍奇金淋巴瘤及其各个亚型都没有持续的或明显的保护作用。研究人员说，“我们观察到了阳光/紫外线照射对非霍奇金淋巴瘤及其各个亚型的持续的保护作用，但是饮食中维生素D摄取和血清/血浆25(OH)D水平与非霍奇金淋巴瘤的相关性却不一致或不显著。”
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