11q高级别淋巴瘤用R CHOEP，还是DA EPOCH-R方案好？

小清晰 · 发表于 2024-8-20 15:26:05

我的病情，派特分期2期，ipi 评分0分，骨髓流式没有侵袭，染色体没有问题。我的主治医生很强势的用R CHOEP，然后喊我六个疗程后移植。我自己的想法是用强一点的方案，后面不用移植！请大神帮我分析一下，感谢@橙色雨丝 @洪飞

橙色雨丝 · 发表于 2024-8-20 15:40:46

NCCN指南是这么说的：Most common karyotype is MYC rearrangement as a sole abnormality. There is an uncommon variant of BL without MYC rearrangement but with 11q aberration (LBCL with 11q aberration [ICC]; HGBL with 11q aberrations [WHO5]). Optimum management of this rare subtype is undefined, though it is most often treated like typical BL。这种类型的最佳治疗路径待定，但大多数时候参照伯基特淋巴瘤来治疗。

小清晰 · 发表于 2024-8-20 16:17:34

橙色雨丝发表于 2024-08-20 15:40
NCCN指南是这么说的：Most common karyotype is MYC rearrangement as a sole abnormality. There is an uncommon variant of BL without MYC rearrangement but with 11q aberration (LBCL with 11q aberration [ICC]; HGBL with 11q aberrations [WHO5]). Optimum management of this rare subtype is undefined, though it is most often treated like typical BL。这种类型的最佳治疗路径待定，但大多数时候参照伯基特淋巴瘤来治疗。

谢谢大神，就是用DA EPOCH-R方案！

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