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发表于 2017-5-15 00:46:56
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来自: 中国河南郑州
橙色雨丝 发表于 2017-5-14 14:34 
我十几年前在美国的时候突然犯了胃病,去当地一家医院做过一次胃镜,确实不必预先交钱,没有保险也只是记下 ...
我也看到这样一篇
这个是ASH年会10号
Health Services and Outcomes Research: Outcomes Research in Hematological Disorders专场的报告!
medscape报道了新闻,现在把新闻(部分翻译)和报告的摘要贴给大家!
News :First Study Ever of Long-Term Problems After HCT
December 10, 2011 (San Diego, California) — Hematopoietic cell transplant (HCT) offers the only potential for a cure for many hematological cancers; however, although the cancer may be cured by the transplant, the recipients remain at risk for psychological and chronic health conditions.
造血干细胞移植是治愈很多血液肿瘤的唯一可能方法。然而,移植虽然治愈了肿瘤,但患者移植后的长期健康状况及心理仍存在风险。
"It's important to realize that once a transplant is over, it's not really over," commented Stephanie J. Lee, MD, MPH, professor of medicine at the University of Washington School of Medicine in Seattle. She was speaking here at the American Society of Hematology (ASH) 53rd Annual Meeting and commented on a study that followed-up transplant survivors for more than 10 years.
认识到移植完成并不意味着结束这一点很重要,华盛顿大学西雅图医学院的医学博士、公共卫生硕士Stephanie J. Lee评论道。
The study, the first of its kind, found that the burden of long-term physical and emotional morbidity experienced by survivors 10 or more years after their transplant is substantial, and that these individuals require high use of specialized healthcare.
作为此类研究的先驱,研究人员发现,那些10年或10年以上的移植生存者在身体及心理上都存在巨大压力,急需专业护理。
The authors found that 74% of HCT survivors reported at least 1 chronic health condition compared with 29% of their siblings (P < .001). In addition, 25% of the survivors also reported severe/life-threatening conditions vs only 8% of the siblings (P < .001).
作者发现, 74%的移植生存者至少有一种慢性疾病,而在其兄弟姐妹中这一机率是29%(P < .001)。另外,移植生存者出现生命危急情况的机率是25%也远高于其手足的8%(P < .001)。
"Transplant has now being going on for many decades, and we are constantly working in the short-term to make transplant better, but it's important that we look at the long-term effects on survivors as well," Dr. Lee commented at a press briefing that highlighted the results of the study. "Patients need to be aware that they are at high risk for this. They need preventive care and survivorship care, and as a society we need to realize that they will need long-term treatment."
移植已经进行了几十年,我们一直致力于如何使移植得短期结果更好,但现在我们也应当注意生存者的长期影响。Dr. Lee在研究结果公布时说。患者需要了解他们存在这样的风险,需要采取预防措施和关注,而我们也应当认识到他们将需要长期的治疗。
The study's senior author, Smita Bhatia, MD, MPH, director of the Center for Cancer Survivorship and BMT Long-Term Follow-up Program at City of Hope in Duarte, California, noted that despite the high rate of long-term and potentially lethal complications, "we need to remember that bone marrow transplant and HCT continue to be a lifesaving, and possibly the only, curative option for a large number of hematologic patients."
文章的通讯作者,癌症存活者及骨髓移植长期随访计划理事医学博士、公共卫生硕士Smita Bhatia指出,尽管长期或潜在的并发症致命风险很高,对大量血液疾病患者来说,骨髓移植及HCT仍可能是唯一能够挽救生命及治愈疾病的方法。
However, 40% of patients, if they survive the first 10 years post transplant, may develop severe, life-threatening conditions, or even die from these illnesses, she added. "The main thing that we want to take away from this is that transplanting physicians, third-party payers, as well as patients and their families, are aware of these findings,"
然而,40%移植后生存10年的患者可能面临严重的危及生命的情况甚至因此死亡,她补充说。我们希望移植专家、保险公司及患者、家属应当知道这些问题。
Dr. Bhatia also pointed out that "we do not want to lose these patients in terms of long-term follow-up."
Dr. Bhatia还指出,我们不希望在长期的随访中失去这些患者。应当建立诊所以便于这些患者能够得到积极的随访,尽早防御并发症、减少发病率。
Clinics need to be established where the patients can be followed-up to aggressively screen these patients, detect these complications early, and thus reduce the morbidity rate, she said.
Not Well Studied
Can-Lan Sun, PhD, who presented the results of the study at the briefing and is the first author of the paper, explained that high-intensity therapeutic exposures, as well as prolonged immunosuppression regimens, can increase the risk for long-term complications after HCT, which in turn increases the specialized healthcare needs of this population. In previous research conducted by D
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